{"id":698,"date":"2023-12-06T19:58:05","date_gmt":"2023-12-06T19:58:05","guid":{"rendered":"https:\/\/cellandcelldivision.com\/?p=698"},"modified":"2023-12-06T19:58:06","modified_gmt":"2023-12-06T19:58:06","slug":"page-155","status":"publish","type":"post","link":"https:\/\/cellandcelldivision.com\/?p=698","title":{"rendered":"Page 155"},"content":{"rendered":"\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"533\" height=\"468\" src=\"https:\/\/cellandcelldivision.com\/wp-content\/uploads\/2023\/12\/image-8.png\" alt=\"\" class=\"wp-image-711\" srcset=\"https:\/\/cellandcelldivision.com\/wp-content\/uploads\/2023\/12\/image-8.png 533w, https:\/\/cellandcelldivision.com\/wp-content\/uploads\/2023\/12\/image-8-300x263.png 300w\" sizes=\"(max-width: 533px) 100vw, 533px\" \/><\/figure>\n\n\n\n<pre class=\"wp-block-verse has-text-align-center\">Figure 2\u201378. Properties of 5-bromouracil (a) and 2-aminopurine (b) \r\nrelevant to the formation of \u201cincorrect\u201d nucleotide pairs with the bases of \r\nDNA. Hydrogen atoms are denoted by black circles, and the bonds \r\nbetween them \u2014 by dotted line (After Hayes, 1965). <\/pre>\n\n\n\n<p class=\"has-text-align-center\">Under the action of different chemical mutagen factors the bases of<br>DNA can undergo a modification that leads to inducing of mutations. For<br>example, nitrous acid (HNO\u2082) causes an oxidative deamination of the<br>bases, at that amino groups are substituted for keto groups. Thus, cytosine<br>is transformed into uracil, adenine \u2014 into hypoxantine, and guanine \u2014 into<br>xantine. Thymine is the only, that is not a subject to deamination since it<br>lacks amino group, and contains a keto group (Fig. 2\u201379). At that uracil<br>binds adenine, and xantine and hypoxantine \u2014 cytosine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Figure 2\u201378. Properties of 5-bromouracil (a) and 2-aminopurine (b) relevant to the formation of \u201cincorrect\u201d nucleotide pairs with the bases of DNA. Hydrogen atoms are denoted by black circles, and the bonds between them \u2014 by dotted line (After Hayes, 1965). Under the action of different chemical mutagen factors the bases ofDNA can undergo a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[6],"tags":[],"class_list":["post-698","post","type-post","status-publish","format-standard","hentry","category-book"],"_links":{"self":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts\/698","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=698"}],"version-history":[{"count":1,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts\/698\/revisions"}],"predecessor-version":[{"id":713,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts\/698\/revisions\/713"}],"wp:attachment":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=698"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=698"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=698"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}