{"id":851,"date":"2023-12-11T21:36:47","date_gmt":"2023-12-11T21:36:47","guid":{"rendered":"https:\/\/cellandcelldivision.com\/?p=851"},"modified":"2023-12-11T21:36:47","modified_gmt":"2023-12-11T21:36:47","slug":"page-206","status":"publish","type":"post","link":"https:\/\/cellandcelldivision.com\/?p=851","title":{"rendered":"Page 206"},"content":{"rendered":"\n<p class=\"has-text-align-center\">factors \u2014 nutrient substances, temperature, pH of the medium, potential<br>genetic and energetic possibilities of the cells, etc. It is difficult to ensure<br>them simultaneously, especially in natural conditions. For example, in<br>case of changing only one of the factors necessary for the development<br>of an optimum synchronized culture of <em>Scenedesmus acutus<\/em> (temperature<br>below 20\u00b0C or pH below 6) under equal other conditions, the cells begin<br>to form two or three nuclei, instead of four, eight or more, and divide very<br>slowly.<br>2. What is the way of realizing the formation of daughter cells and the<br>distribution of cytoplasm in the mother cell, i.e. whether it occurs<br>immediately after each nuclear division or after reaching a \u201ccrucial\u201d<br>number of nuclei, when the mother cell will start releasing the new<br>generation of daughter cells?<br>This questions has been attracted the attention already at the time of<br>Smith (1914), then of Mazia (1963), Pickett-Heaps (1975) and many other<br>investigators. But even now it is still unclear. According to Pickett-Heaps<br>\u201cthe divisions that occur after the completion of mitosis have proved to be<br>most difficult regarding ultrastructure studies and they are largely resisted<br>analyses\u201d.<br>3. What are the reasons and mechanisms determining the \u201cdecision\u201d<br>of a nucleus to start a subsequent division or not to divide and form a<br>daughter cell?<br>This is a real \u201cmystery\u201d of cell biology, and it will be very hard to be<br>solved. Here is the key to the asynchronous division approved in the<br>course of evolution. In my opinion it is realized asynchronously,<br>consecutively on the principle \u201cnucleus \u2014 cell\u201d. Violating this principle<br>leads to multinuclear cells, mentioned in the previous Section 3. 3 \u2014<br>symplasts, osteoclasts, HeLa-cells, etc., where cell division does not<br>proceed normally.<br>Accepting the asynchronous nuclear and cell division as a natural<br>biological process (Nicolov, 1997 a) gives rise to the necessity to change<br>the trends and methods of cell research. The reason for such a mode of<br>division should be looked for mainly in the genetic material, in eventual<br>differences between the copies of DNA-replication and in the energetic<br>possibilities of cells, acquired as a result of the metabolic processes in<br>them.<br>Let pay attention to the energetic aspect of the question, that could<br>be the decisive evolutionary factor determining the way of realizing the<br>reproduction of nuclei and cells in time. It is known that every biological<br>process needs some energy. Undoubtedly, nuclear and cell division is<br>connected with such processes. If in one cell of <em>Scenedesmus acutus<\/em> or<br><em>Clorella vulgaris <\/em>there are four or eight nuclei and they are to reproduce<br>simultaneously, i.e. synchronously in eight or sixteen, respectively, much<br>more energy for a given time will be necessary, than if that proceeds<\/p>\n","protected":false},"excerpt":{"rendered":"<p>factors \u2014 nutrient substances, temperature, pH of the medium, potentialgenetic and energetic possibilities of the cells, etc. It is difficult to ensurethem simultaneously, especially in natural conditions. For example, incase of changing only one of the factors necessary for the developmentof an optimum synchronized culture of Scenedesmus acutus (temperaturebelow 20\u00b0C or pH below 6) under [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[6],"tags":[],"class_list":["post-851","post","type-post","status-publish","format-standard","hentry","category-book"],"_links":{"self":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts\/851","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=851"}],"version-history":[{"count":2,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts\/851\/revisions"}],"predecessor-version":[{"id":857,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=\/wp\/v2\/posts\/851\/revisions\/857"}],"wp:attachment":[{"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=851"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=851"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cellandcelldivision.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=851"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}